The BBC's director of news, Helen Boaden, and her deputy, Stephen Mitchell, have stepped aside as a result of a botched Newsnight report which contributed to the resignation of director-general George Entwistle.
Their moves came as a report into the Newsnight programme which mistakenly implicated Lord McAlpine in a sex abuse scandal was produced.
The BBC's head of newsgathering, Fran Unsworth, and Ceri Thomas, the editor of the Radio 4 Today programme, are to fill in for Ms Boaden and Mr Mitchell temporarily.
The changes - which also include a change in the "chain of command" dealing with all BBC output - were announced in response to the report into Newsnight by Ken MacQuarrie, the director of BBC Scotland.
It comes in the wake of the resignation of Mr Entwistle on Saturday, which has left the embattled corporation in crisis, amid calls for BBC Trust chairman Lord Patten to follow suit.
The response to the report has been one of the first issues to be tackled by acting director-general Tim Davie as he prepares to rebuild trust in the corporation.